Michael and his group give Bellick the slip, forcing Bellick to relinquish command to the FBI; Special Agent Mahone cracks the code to Michael's escape plans; and T-Bag takes extreme measures to get his hand back.
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Mahone uses LJ as bait to trap Lincoln and Michael; T-Bag gets reunited with his severed hand, and a desperate courthouse rescue brings the brothers face to face with their pursuer.
Michael’s most valuable asset falls into Mahone’s hands; the Governor makes a shocking announcement to Sara; and Sucre and C-Note try to reunite with their families, no matter what the cost.
Bellick captures Michael and his team, but it’s not the police reward he’s after; Nika sets someone up, but we don’t know who; and Abruzzi’s need for revenge will force him to pay the ultimate price.
The brothers finally arrive in Utah, only to discover they’re not alone; Sucre is left waiting at the alter; C-Note leaps for his life; and the Double K Ranch will not give up it’s secrets easily.
With the millions buried somewhere under a housing development, Michael must coax the map out of T-Bag’s head and figure a way in; Mahone zeros in ever closer to his prey; and one of the escapees comes to the end of the line.
The escapees find the hidden treasure, but Sucre has other plans; Lincoln risks everything to get to LJ; the Company puts a hit on Sara; and Mahone puts Tweener to the ultimate test.
With the five million gone and the police closing in, Michael and Sucre’s only chance of escape is across the river...but the water conceals a deadly trap; Lincoln reunites with LJ; and Sara and Kellerman race to piece together the clues Michael left behind.
Michael pays a visit to Mahone's ex-wife, and pieces together his dark secret; Bellick ambushes T-Bag, and he’ll stop at nothing to learn where the money is; and Lincoln and LJ appear to come to the end of the line.
Michael and Sara reunite, but their time together is cut short as Mahone finally catches up to them; on the road with LJ, Lincoln meets his father; and Bellick finally gets T-Bag to give up his secret.... the hard way.
To reunite with Michael, Lincoln must leave LJ behind; Michael's plan to obtain a getaway plane falls apart; T-Bag escapes the police but pays a devastating price; and Kellerman tortures Sara to get what he wants.
Sara breaks free from her tormentor; Aldo makes his peace with Michael but pays the ultimate price; and Michael and Lincoln decide to stop running and take a stand against their pursuers.
Bellick returns to Fox River, but not the way he planned; Michael and Lincoln are en route to join him, but Mahone and Kellerman will do everything in their power to make certain the brothers are dead on arrival; and T-Bag pays a surprise visit to Mrs. Hollander.
Kellerman brings Michael and Lincoln face to face with Steadman, but their plans unravel in a heartbeat; Bellick crosses the wrong prisoner at Fox River; and "Uncle Teddy" T-Bag terrorizes the Hollanders with his own warped idea of "family."
While on the run with Kellerman, Michael and Lincoln reveal their story on national television; Michael gets a coded message to Sara which could reunite them once again; and Bellick gives Mahone a valuable clue that may jeopardize their entire plan.
When the diner they are eating in is robbed, C-Note must weigh his daughter’s health against the life of a young waitress; Kellerman solves the riddle of Sara’s key, but it could be a trap for Michael and Lincoln; and Mahone makes Bellick and Haywire an offer they can’t refuse.
Michael and Sara turn to Henry Pope to retrieve the information that will topple The Company; An escapee must chose between his daughter and his friends; T-Bag brings the Hollander family to his childhood home.
Michael, Lincoln, and Sara finally hear the proof that can set Lincoln free, but they'll need another ally on the inside to get the truth heard; T-Bag seeks psychiatric help, and to secure his family's safety; and C-Note must make the ultimate sacrifice.
Michael pays the consequences, but finally comes face to face with the president; An unlikely alliance forms between Bellick and Sucre; T-Bag loses his money and C-Note's offered an out if he double-crosses Mahone.
With the brothers preparing to sail away to freedom, Sara’s forced to sacrifice herself to ensure their safety; T-Bag leaves a trail of death south of the border; and C-Note finally receives the offer he’s been hoping for.
Sara goes to trial; Michael is determined to get the five million, and to put an end to T-Bag's reign of terror; Kellerman faces his demons; and Lincoln and Mahone face off.
Michael attempts to save Lincoln and himself from Mahone’s double-cross; a surprise witness at Sara's trial changes everything; Sucre puts his life on the line to find Maricruz; and T-Bag chooses the wrong side.